{"created":"2023-05-15T09:48:47.393019+00:00","id":11719,"links":{},"metadata":{"_buckets":{"deposit":"7ede0bc9-bda9-42e5-bf05-ac123aa33efb"},"_deposit":{"created_by":11,"id":"11719","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"11719"},"status":"published"},"_oai":{"id":"oai:kagawa-u.repo.nii.ac.jp:00011719","sets":["13:40"]},"author_link":["4107"],"item_10006_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"非小細胞肺癌の細胞診における腺癌と扁平上皮癌の鑑別に有用な細胞学的構造所見の検討","subitem_alternative_title_language":"ja"}]},"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2023-03-24"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"香川大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"Kagawa University"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"16201","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Introduction: This study aimed to clarify the diagnostic structural features in cytology specimens that are useful in subtyping non-small cell lung carcinoma (NSCLC) into adenocarcinoma (ADC) and squamous cell carcinoma (SQCC).","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"Methods: Cytology specimens (n = 233) of NSCLCs, which included ADCs (n = 149) and SQCCs (n = 84), were analyzed. The following cytological features were evaluated: isolated cell, flat sheet, three-dimensional cluster with irregular arrangement, papillary-like structure, micropapillary-like structure, acinar-like structure, palisading pattern, protrusion of nuclei at the periphery of the cluster, honeycomb pattern, streaming arrangement, three-dimensional sheets with regular arrangement, flattening at the periphery of the cluster, fuzzy pattern at the periphery of the cluster, and mutual inclusion.","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"Results: ADCs exhibited significantly higher frequencies of flat sheet (p < 0.001), papillary-like structure (p < 0.001), micropapillary-like structure (p = 0.028), acinar-like structure (p < 0.001), and protrusion of nuclei at the periphery of the cluster (p < 0.001) than SQCCs. The latter exhibited significantly higher frequencies of streaming arrangement (p < 0.001), three-dimensional sheets with regular arrangement (p < 0.001), flattening at the periphery of the cluster (p < 0.001), fuzzy pattern at the periphery of the cluster (p < 0.001), and mutual inclusion (p < 0.001) than ADCs.","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"Discussion: Cytological structural features, such as flat sheet, papillary-like structure, micropapillary-like structure, acinar-like structure, and protrusion of nuclei at the periphery of the cluster, indicated ADC, whereas streaming arrangement, three-dimensional sheets with regular arrangement, flattening at the periphery of the cluster, fuzzy pattern at the periphery of the cluster, and mutual inclusion indicated SQCC. Paying attention to these cytological structural features can enable the accurate subtyping of NSCLC into ADC and SQCC.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第822号"}]},"item_10006_relation_15":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1159/000528882","subitem_relation_type_select":"DOI"}}]},"item_10006_relation_22":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"36592626","subitem_relation_type_select":"PMID"}}]},"item_10006_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2023 S. Karger AG, Basel","subitem_rights_language":"en"}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_fa2ee174bc00049f","subitem_version_type":"P"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"井上, 耕佑","creatorNameLang":"ja"},{"creatorName":"イノウエ, コウスケ","creatorNameLang":"ja-Kana"},{"creatorName":"Inoue, Kosuke","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-04-24"}],"displaytype":"detail","filename":"Med_A822.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","objectType":"fulltext","url":"https://kagawa-u.repo.nii.ac.jp/record/11719/files/Med_A822.pdf"},"version_id":"bb2b6113-7d6c-4b07-8cc9-7453549b32da"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-04-24"}],"displaytype":"detail","filename":"Med_A822_abstract.pdf","filesize":[{"value":"118.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"内容の要旨","objectType":"abstract","url":"https://kagawa-u.repo.nii.ac.jp/record/11719/files/Med_A822_abstract.pdf"},"version_id":"381a3405-3c78-4e46-884c-b671e449f77c"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2023-04-24"}],"displaytype":"detail","filename":"Med_A822_result.pdf","filesize":[{"value":"112.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"審査の結果の要旨","objectType":"other","url":"https://kagawa-u.repo.nii.ac.jp/record/11719/files/Med_A822_result.pdf"},"version_id":"077c95e6-38a0-4744-a6ad-2966eea045ed"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Cytology","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Non-small cell lung carcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Cytological structural features","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Adenocarcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Squamous cell carcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Subtyping of non-small cell lung carcinoma into adenocarcinoma and squamous cell carcinoma by cytological structural features","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Subtyping of non-small cell lung carcinoma into adenocarcinoma and squamous cell carcinoma by cytological structural features","subitem_title_language":"en"}]},"item_type_id":"10006","owner":"11","path":["40"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2023-04-24"},"publish_date":"2023-04-24","publish_status":"0","recid":"11719","relation_version_is_last":true,"title":["Subtyping of non-small cell lung carcinoma into adenocarcinoma and squamous cell carcinoma by cytological structural features"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-10-16T02:32:40.142354+00:00"}