{"created":"2023-05-15T09:41:08.229764+00:00","id":150,"links":{},"metadata":{"_buckets":{"deposit":"60790914-049a-4b4c-8361-81d136058df5"},"_deposit":{"created_by":11,"id":"150","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"150"},"status":"published"},"_oai":{"id":"oai:kagawa-u.repo.nii.ac.jp:00000150","sets":["13:40"]},"author_link":["3143"],"item_10006_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"ビスホスホネートに対する顎骨の骨代謝の変化：骨シンチグラフィー定量分析","subitem_alternative_title_language":"ja"}]},"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2020-06-25"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"香川大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"Kagawa University"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"16201","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We examined the changes in the bone metabolism of the jaw in response to BP treatment, and we used bone SPECT-CT to analyze the site-specific bone metabolism between the jaw and other sites of bone. We compared the changes in the bone metabolism of each part of bone in response to BP treatment by performing a quantitative analysis of bone scintigraphy images between patients treated with low-dose BP for osteoporosis (LBP group; n = 17), those treated with high-dose BP for metastatic bone tumor (HBP group; n = 11), and patients with other oral disease who required bone scintigraphy, with no history of BP treatment (control group; n = 40). The study endpoint was the mean standardized uptake value (SUV) of the uptake of Tc-99 m methylene diphosphonate (MDP) in each group. The mean SUVs of the HBP group were significantly lower at the axial bone of the cervical vertebra, thoracic vertebra, sternum, and rib compared to those of the LBP and control groups. The LBP group's mean SUV was significantly higher at the temporal bone, the anodontia part of the alveolar bone in maxilla, the vital teeth part of alveolar bone in the mandible, and the temporomandibular joint. There was no significant difference among the three groups at the mandibular angle and mandibular ramus. Our analyses revealed that the bone metabolism of the jaw and temporal bone in the BP-treated patients was enhanced, and no suppression of bone remodeling in the jaw by BP was observed.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第753号"}]},"item_10006_relation_15":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1007/s10266-020-00503-1","subitem_relation_type_select":"DOI"}}]},"item_10006_relation_16":{"attribute_name":"他の資源との関係","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"This is the Accepted Version of the following article: Bone metabolism of the jaw in response to bisphosphonate: A quantitative analysis of bone scintigraphy images; Odontology; 2020 Mar 5. Online ahead of print; doi:10.1007/s10266-020-00503-1, which has been published in final form at https://link.springer.com/article/10.1007/s10266-020-00503-1 ."}]}]},"item_10006_relation_22":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"32140951","subitem_relation_type_select":"PMID"}}]},"item_10006_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 2020 Springer Nature Switzerland AG. Part of Springer Nature.","subitem_rights_language":"en"},{"subitem_rights":"Embergo Expiration Date: 2021 Mar. 5.","subitem_rights_language":"en"}]},"item_10006_text_30":{"attribute_name":"KEID","attribute_value_mlt":[{"subitem_text_value":"29003"}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_fa2ee174bc00049f","subitem_version_type":"P"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAlternatives":[{"creatorAlternative":"澤井, 史","creatorAlternativeLang":"ja"}],"creatorNames":[{"creatorName":"中井, 史","creatorNameLang":"ja"},{"creatorName":"ナカイ, フミ","creatorNameLang":"ja-Kana"},{"creatorName":"Nakai, Fumi ","creatorNameLang":"en"}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-03-08"}],"displaytype":"detail","filename":"Med_A753 (Accepted Version).pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文","objectType":"fulltext","url":"https://kagawa-u.repo.nii.ac.jp/record/150/files/Med_A753 (Accepted Version).pdf"},"version_id":"0e71965e-1a17-4a22-8f5c-6ac6442c6733"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-12"}],"displaytype":"detail","filename":"Med_A753_abstract.pdf","filesize":[{"value":"122.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"内容の要旨","objectType":"abstract","url":"https://kagawa-u.repo.nii.ac.jp/record/150/files/Med_A753_abstract.pdf"},"version_id":"b6e87f9c-dc42-45d9-a3e5-23f9a2f606ac"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-12"}],"displaytype":"detail","filename":"Med_A753_result.pdf","filesize":[{"value":"87.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"審査の結果の要旨","objectType":"other","url":"https://kagawa-u.repo.nii.ac.jp/record/150/files/Med_A753_result.pdf"},"version_id":"db866ed6-6e08-41d1-92db-fac1a4214f40"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Bisphosphonate","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Bone metabolism","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Bone scintigraphy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Jaw","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"SUV","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Bone metabolism of the jaw in response to bisphosphonate : A quantitative analysis of bone scintigraphy images","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Bone metabolism of the jaw in response to bisphosphonate : A quantitative analysis of bone scintigraphy images","subitem_title_language":"en"}]},"item_type_id":"10006","owner":"11","path":["40"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-07-10"},"publish_date":"2020-07-10","publish_status":"0","recid":"150","relation_version_is_last":true,"title":["Bone metabolism of the jaw in response to bisphosphonate : A quantitative analysis of bone scintigraphy images"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-11-24T01:45:17.998872+00:00"}