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Effect of quantitative values on shortened acquisition duration in brain tumor ¹¹C-methionine PET/CT
https://kagawa-u.repo.nii.ac.jp/records/2000378
https://kagawa-u.repo.nii.ac.jp/records/20003789de068f9-d052-4655-89e7-64c346127d06
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||||||
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公開日 | 2024-04-11 | |||||||||||||
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タイトル | Effect of quantitative values on shortened acquisition duration in brain tumor ¹¹C-methionine PET/CT | |||||||||||||
言語 | en | |||||||||||||
言語 | ||||||||||||||
言語 | eng | |||||||||||||
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資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||||||
資源タイプ | doctoral thesis | |||||||||||||
アクセス権 | ||||||||||||||
アクセス権 | open access | |||||||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||||
著者 |
森本, 真壽
× 森本, 真壽
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内容記述タイプ | Abstract | |||||||||||||
内容記述 | Background: The amount of signal decreases when the acquisition duration is shortened. However, it is not clear how this affects the quantitative values. This study aims to clarify the effect of acquisition time shortening in brain tumor PET/CT using 11C-methionine on the quantitative values. | |||||||||||||
言語 | en | |||||||||||||
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内容記述タイプ | Abstract | |||||||||||||
内容記述 | Method: This study was a retrospective analysis of 30 patients who underwent clinical 11C-methionine PET/CT examination. PET images were acquired in list mode for 10 min. PET images of acquisition duration from 1 to 10 min with 1-min step were reconstructed. We examined the effect on the quantitative values of acquisition duration. We placed a volume of interest to include the entire tumor and regions of interest in the shape of a large crescent in the contralateral hemisphere in 5 contiguous axial slices as normal tissue. Quantitative values examined were maximum, peak, and mean standardized uptake values (SUVmax, SUVpeak, SUVmean), metabolic tumor volume (MTV), and maximum tumor to normal tissue ratio (TNRmax), with each duration compared to that with 10 min. | |||||||||||||
言語 | en | |||||||||||||
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内容記述タイプ | Abstract | |||||||||||||
内容記述 | Results: SUVmax, MTV, and TNRmax showed the highest values due to the effects of statistical noise when the acquisition time was 1 min. These values were stable when the acquisition duration was > 6 min. SUVpeak and SUVmean showed mostly consistent values regardless of duration. | |||||||||||||
言語 | en | |||||||||||||
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内容記述タイプ | Abstract | |||||||||||||
内容記述 | Conclusions: SUVmax, MTV, and TNRmax are affected by acquisition time. If the acquisition duration was > 6 min, the fluctuation could be suppressed within 5% in these quantitative values. However, SUVpeak was suggested to be a robust index regardless of the acquisition duration. | |||||||||||||
言語 | en | |||||||||||||
学位名 | ||||||||||||||
言語 | ja | |||||||||||||
学位名 | 博士(医学) | |||||||||||||
学位授与機関 | ||||||||||||||
識別子Scheme | kakenhi | |||||||||||||
識別子 | 16201 | |||||||||||||
言語 | ja | |||||||||||||
機関名 | 香川大学 | |||||||||||||
言語 | en | |||||||||||||
機関名 | Kagawa University | |||||||||||||
学位授与年月日 | ||||||||||||||
学位授与年月日 | 2024-03-24 | |||||||||||||
学位授与番号 | ||||||||||||||
学位授与番号 | 甲第857号 | |||||||||||||
権利 | ||||||||||||||
言語 | en | |||||||||||||
権利情報 | © The Author(s). 2021 | |||||||||||||
権利 | ||||||||||||||
言語 | en | |||||||||||||
権利情報Resource | https://creativecommons.org/licenses/by/4.0/ | |||||||||||||
権利情報 | This is an open access article distributed under the terms of the Creative Commons CC BY license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||||||||||
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識別子タイプ | PMID | |||||||||||||
関連識別子 | 33788057 | |||||||||||||
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関連タイプ | isVersionOf | |||||||||||||
識別子タイプ | DOI | |||||||||||||
関連識別子 | https://doi.org/10.1186/s40658-021-00379-2 | |||||||||||||
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関連タイプ | hasVersion | |||||||||||||
識別子タイプ | URI | |||||||||||||
関連識別子 | http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8012475/ | |||||||||||||
著者版フラグ | ||||||||||||||
出版タイプ | P | |||||||||||||
出版タイプResource | http://purl.org/coar/version/c_fa2ee174bc00049f | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | 11C-methionine | |||||||||||||
キーワード | ||||||||||||||
言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | Acquisition duration | |||||||||||||
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言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | Statistical noise | |||||||||||||
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言語 | en | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | SUVpeak |