{"created":"2025-02-28T09:43:41.797980+00:00","id":2000745,"links":{},"metadata":{"_buckets":{"deposit":"3b115171-d77b-42d4-880c-baf4010b93fe"},"_deposit":{"created_by":11,"id":"2000745","owner":"11","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"2000745"},"status":"published"},"_oai":{"id":"oai:kagawa-u.repo.nii.ac.jp:02000745","sets":["2"]},"author_link":["4470","2667"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2022-10-14","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicNumberOfPages":"10","bibliographicPageStart":"2572","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"Biomedicines","bibliographic_titleLang":"en"}]}]},"item_10001_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"An unhealthy diet can lead to the development of metabolic disorders. C-reactive protein (CRP) has been reported to be an inflammatory component of metabolic disorders. Additionally, reduced adiponectin (APN) levels is known as a predictor of metabolic disorders. We report on the beneficial effects of NBF1, an algal fiber-rich formula, on CRP, APN, and diabetes markers. Additionally, associations between dietary nutrients, CRP, and APN were investigated. A dietary survey that used a brief self-administered diet history questionnaire, a validated 58-item fixed-portion-type questionnaire, and a 4-week placebo-controlled dietary intervention were carried out. The latter consisted of a twice daily intake of 3 g of sujiaonori alga-based powder as a supplement (NBF1, n = 16), whereas the placebo group received the same amount of corn starch powder (n = 15). CRP and APN levels were assayed by ELISA. Clinical cases comprising three subjects with metabolic disorders treated with NBF1, including two type 2 diabetes mellitus patients and one subject with hypercholesterolemia, are also reported. They received 2.1g NBF1 once daily for 12 weeks. Intakes of algal fiber and n-3 PUFA were positively associated with the increase of APN, and n-3PUFA intake was inversely associated with CRP. All cases had improved metabolic health profile.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDP","subitem_publisher_language":"en"}]},"item_10001_relation_12":{"attribute_name":"論文ID（NAID）","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://cir.nii.ac.jp/crid/1360017279869756800","subitem_relation_type_select":"CRID"}}]},"item_10001_relation_13":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"36289836","subitem_relation_type_select":"PMID"}}]},"item_10001_relation_18":{"attribute_name":"他の資源との関係","attribute_value_mlt":[{"subitem_relation_type":"hasVersion","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9599379/","subitem_relation_type_select":"URI"}}]},"item_10001_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2022 by the authors. Licensee MDPI, Basel, Switzerland.","subitem_rights_language":"en"},{"subitem_rights":"This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.","subitem_rights_language":"en","subitem_rights_resource":"https://creativecommons.org/licenses/by/4.0/"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2227-9059","subitem_source_identifier_type":"EISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1691368617353":{"attribute_name":"識別子","attribute_value_mlt":[{"subitem_identifier_type":"DOI","subitem_identifier_uri":"https://doi.org/10.3390/biomedicines10102572"}]},"item_1691372060236":{"attribute_name":"助成情報","attribute_value_mlt":[{"subitem_funder_identifiers":{"subitem_funder_identifier":"https://isni.org/isni/0000000404070751","subitem_funder_identifier_type":"ISNI"},"subitem_funder_names":[{"subitem_funder_name":"高知県","subitem_funder_name_language":"ja"},{"subitem_funder_name":"Kochi Prefecture","subitem_funder_name_language":"en"}],"subitem_funding_streams":[{"subitem_funding_stream":"Kochi Prefecture Local Development Fund 2015","subitem_funding_stream_language":"en"}]}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ngatu, Nlandu Roger","creatorNameLang":"ja"},{"creatorName":"ガツ, ランドウ","creatorNameLang":"ja-Kana"},{"creatorName":"Ngatu, Nlandu Roger","creatorNameLang":"en"}],"familyNames":[{"familyName":"Ngatu","familyNameLang":"ja"},{"familyName":"ガツ","familyNameLang":"ja-Kana"},{"familyName":"Ngatu","familyNameLang":"en"}],"givenNames":[{"givenName":"Nlandu Roger","givenNameLang":"ja"},{"givenName":"ランドウ","givenNameLang":"ja-Kana"},{"givenName":"Nlandu Roger","givenNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"4470","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000040635249","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/1000040635249"},{"nameIdentifier":"40635249","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=40635249"},{"nameIdentifier":"ngatu-nlandu","nameIdentifierScheme":"researchmap","nameIdentifierURI":"https://researchmap.jp/ngatu-nlandu"},{"nameIdentifier":"3154620803944591419","nameIdentifierScheme":"VIAF","nameIdentifierURI":"https://viaf.org/viaf/3154620803944591419"},{"nameIdentifier":"0000-0002-8847-3667","nameIdentifierScheme":"ORCID","nameIdentifierURI":"https://orcid.org/0000-0002-8847-3667"}]},{"creatorNames":[{"creatorName":"Hirao, Tomohiro","creatorNameLang":"en"},{"creatorName":"平尾, 智広","creatorNameLang":"ja"},{"creatorName":"ヒラオ, トモヒロ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Hirao","familyNameLang":"en"},{"familyName":"平尾","familyNameLang":"ja"},{"familyName":"ヒラオ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Tomohiro","givenNameLang":"en"},{"givenName":"智広","givenNameLang":"ja"},{"givenName":"トモヒロ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2667","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000020325335","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/1000020325335"},{"nameIdentifier":"20325335","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=20325335"},{"nameIdentifier":"thirao2020","nameIdentifierScheme":"researchmap","nameIdentifierURI":"https://researchmap.jp/thirao2020"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-02-28"}],"displaytype":"detail","fileDate":[{"fileDateType":"Issued","fileDateValue":"2022-10-14"}],"filename":"biomedicines-10-02572","format":"text/html","licensetype":"license_0","url":{"objectType":"fulltext","url":"https://doi.org/10.3390/biomedicines10102572"},"version_id":""}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"adiponectin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"C-reactive protein","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"metabolic marker","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"sujiaonori","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Modulatory effects of NBF1, an algal fiber-rich bioformula, on adiponectin and C-reactive protein levels, and its therapeutic prospects for metabolic syndrome and type-2 diabetes patients","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Modulatory effects of NBF1, an algal fiber-rich bioformula, on adiponectin and C-reactive protein levels, and its therapeutic prospects for metabolic syndrome and type-2 diabetes patients","subitem_title_language":"en"}]},"item_type_id":"10001","owner":"11","path":["2"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2025-02-28"},"publish_date":"2025-02-28","publish_status":"0","recid":"2000745","relation_version_is_last":true,"title":["Modulatory effects of NBF1, an algal fiber-rich bioformula, on adiponectin and C-reactive protein levels, and its therapeutic prospects for metabolic syndrome and type-2 diabetes patients"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2025-03-21T05:07:25.976026+00:00"}