| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-04-24 |
| タイトル |
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|
タイトル |
Appearance time of blood in the brain as a possible indicator of oxygen extraction fraction: a feasibility study |
|
言語 |
en |
| 言語 |
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|
言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| ID登録 |
|
|
ID登録 |
10.57372/0002000917 |
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ID登録タイプ |
JaLC |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
村尾, 光優
久冨, 信之
三田村, 克哉
則兼, 敬志
真鍋, 悠利
前田, 幸人
山本, 由佳
畠山, 哲宗
西山, 佳宏
|
| 抄録 |
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内容記述タイプ |
Abstract |
|
内容記述 |
Background: Imaging examination of cerebral blood flow (CBF), oxygen extraction fraction (OEF), and metabolic rate of oxygen is crucial for understanding the normal functioning and pathophysiology of the brain. A recently developed method estimates the appearance time of cerebral blood (ATB) pixel-wise from the imaging examination of CBF alone. In this study, we aimed to test the potential of ATB as an indicator of OEF.
Results: We retrospectively reviewed patients (n = 62) with suspected cerebrovascular disorders including steno-occlusive disease who underwent positron emission tomography (PET) with 15O-labelled tracers. Regarding the generated OEF and ATB images, a visual assessment was performed to test the consistency of the elevated OEF and delayed ATB. The OEF and ATB values and the absolute differences between their ipsilateral and contralateral sides were extracted and obtained for the entire hemisphere and the middle, anterior, and posterior cerebral arterial regions. Consistency was observed in 52 PET scans (83.9%) in visual assessment. The OEF and ATB values were moderately correlated (r = 0.553, p < 0.001), and the differences between their ipsilateral and contralateral sides were weakly correlated (r = 0.276, p < 0.001).
Conclusion: Our results indicate the potential of ATB as an indicator of OEF. |
|
言語 |
en |
| 書誌情報 |
en : EJNMMI Research
巻 14,
p. 97-104,
発行日 2024-10-16
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| 出版者 |
|
|
出版者 |
Springer Nature |
|
言語 |
en |
| ISSN |
|
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収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2191-219X |
| 権利 |
|
|
言語 |
en |
|
権利情報 |
© 2024. The Author(s). |
| 権利 |
|
|
言語 |
en |
|
権利情報Resource |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
|
権利情報 |
This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License |
| 助成情報 |
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識別子タイプ |
Crossref Funder |
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助成機関識別子タイプURI |
https://www.crossref.org/services/funder-registry/ |
|
|
助成機関識別子 |
https://doi.org/10.13039/501100001691 |
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|
助成機関名 |
日本学術振興会 |
|
|
言語 |
ja |
|
|
助成機関名 |
Japan Society for the Promotion of Science |
|
|
言語 |
en |
|
|
研究課題番号URI |
https://kaken.nii.ac.jp/ja/grant/KAKENHI-PROJECT-19K17201/ |
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|
研究課題番号 |
19K17201 |
|
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研究課題番号タイプ |
JGN |
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研究課題名 |
脳循環代謝予備能の重症度評価における新規SPECT検査法の開発 |
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言語 |
ja |
| PubMed番号 |
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関連タイプ |
isReferencedBy |
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識別子タイプ |
URI |
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関連識別子 |
https://pubmed.ncbi.nlm.nih.gov/39406936/ |
| 関連サイト |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1186/s13550-024-01160-z |
| 関連サイト |
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関連タイプ |
hasVersion |
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識別子タイプ |
URI |
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関連識別子 |
https://pmc.ncbi.nlm.nih.gov/articles/PMC11480264/ |
| 著者版フラグ |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
15O-labelled tracer |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Appearance time of blood |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Cerebral blood flow |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Oxygen extraction fraction |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Positron emission tomography |
EJNMMI Res_14(1)_L097 (1.6 MB)
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