| Item type |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-09-11 |
| タイトル |
|
|
タイトル |
Tumor location, clinicopathological features, and perioperative and prognostic outcomes in patients who underwent pancreatic resection following neoadjuvant chemoradiotherapy for resectable pancreatic cancer: A retrospective study |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
須藤, 広誠
松川, 浩之
福家, 拓郎
長尾, 美奈
安藤, 恭久
大島, 稔
山名, 浩喜
鎌田, 英紀
小原, 英幹
奥山, 浩之
隈元, 謙介
岡野, 圭一
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Background
/Objective: Preoperative treatment of resectable pancreatic ductal adenocarcinoma (PDAC) is gaining popularity worldwide. However, the characteristics of tumors located in the pancreatic head (Ph), or those in the body or tail (Pbt), after surgery following neoadjuvant chemoradiotherapy (NACRT) remain unclear. This study aimed to evaluate and compare the clinicopathological features, perioperative outcomes, and prognosis of patients with resectable PDAC who underwent NACRT followed by curative pancreatic resection, focusing on distinguishing between Ph and Pbt PDACs. |
|
言語 |
en |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Methods
We included 107 patients with resectable PDAC who underwent curative resection following NACRT between 2009 and 2023. Clinicopathological features, perioperative and prognostic outcomes, recurrence patterns, and prognoses were compared between Ph and Pbt PDAC groups. |
|
言語 |
en |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Results
Tumors were found in the Ph and Pbt in 64 and 43 patients, respectively. Albumin levels and lymphocyte-to-monocyte ratios after NACRT were significantly lower in the Ph group than in the Pbt group. The Pbt group showed significantly higher rates of positive peritoneal lavage cytology and serosal, arterial, and portal vein invasion than the Ph group did. Overall and recurrence-free survival were similar between the two groups. The most common site of initial postoperative recurrence was the lung only in both groups; however, the rate of peritoneal dissemination only was significantly higher in the Pbt group than in the Ph group. |
|
言語 |
en |
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Conclusions
The prognoses based on tumor locations in the Ph and Pbt after surgery following NACRT are similar. Following the resection of resectable Pbt PDAC, the possibility of peritoneal dissemination recurrence should be considered. |
|
言語 |
en |
| 書誌情報 |
en : Pancreatology
巻 24,
号 3,
p. 431-436,
発行日 2024-05-01
|
| 出版者 |
|
|
出版者 |
Elsevier |
|
言語 |
en |
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
1424-3911 |
| 権利 |
|
|
言語 |
en |
|
権利情報 |
© 2024 IAP and EPC. Published by Elsevier B.V. All rights reserved. |
| PubMed番号 |
|
|
関連タイプ |
isVersionOf |
|
|
識別子タイプ |
PMID |
|
|
関連識別子 |
38383175 |
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Chemoradiation |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Pancreatectomy |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Pancreatic ductal adenocarcinoma |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Preoperative treatment |
| キーワード |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Tumor location |
Pancreatology24-3_431-436
