{"created":"2023-05-15T09:41:12.711654+00:00","id":265,"links":{},"metadata":{"_buckets":{"deposit":"74b757e7-69da-4e80-88bb-b921eaf12b3f"},"_deposit":{"created_by":11,"id":"265","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"265"},"status":"published"},"_oai":{"id":"oai:kagawa-u.repo.nii.ac.jp:00000265","sets":["13:40"]},"author_link":["2999"],"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2016-06-28"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"香川大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"Kagawa University"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"16201","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background\nThe ratio of urinary coproporphyrin (UCP) I to total urinary coproporphyrin I and III [UCP {I/(I + III)]] serves as a biomarker of the ATP‐binding cassette, sub‐family C, member 2 (ABCC2) function. The aim of this study was to clarify the characteristics of the developmental pattern of UCP [I/(I + III)] in order to estimate ABCC2 function in children, especially in the neonatal period, by measuring it throughout the entirety of childhood.","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"Method\nMeasurement of UCP [I/(I + III)] was done high‐performance liquid chromatography, using urine samples collected from children from 1 day to 15 years old, involving one sample per child. Urine samples from children with liver and kidney disease and urinary tract infection were excluded.","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"Results\nUCP [I/(I + III)] varied widely in infants younger than 6 months old, and was ≥0.3 in 80% of the infants. In contrast, it decreased to <0.30, the lowest, at 1–2 years old. In the 0–6‐month‐old group, no significant correlation was noted between postnatal age and UCP [I/(I + III)], but a moderate inverse correlation was noted between corrected gestational age and UCP [I/(I + III)].","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"Conclusion\nUCP [I/(I + III)] is inversely correlated with corrected gestational age and is lowest at 1–2 years old. This suggests that ABCC2 activity is correlated with corrected gestational age and is highest at 1–2 years old.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第640号"}]},"item_10006_relation_15":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/ped.12965","subitem_relation_type_select":"DOI"}}]},"item_10006_relation_22":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"26920082","subitem_relation_type_select":"PMID"}}]},"item_10006_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2016 Japan Pediatric Society.","subitem_rights_language":"en"}]},"item_10006_text_30":{"attribute_name":"KEID","attribute_value_mlt":[{"subitem_text_value":"27852"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Kunikata, Jun","creatorNameLang":"en"},{"creatorName":"國方, 淳","creatorNameLang":"ja"},{"creatorName":"クニカタ, ジュン","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Kunikata","familyNameLang":"en"},{"familyName":"國方","familyNameLang":"ja"},{"familyName":"クニカタ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Jun","givenNameLang":"en"},{"givenName":"淳","givenNameLang":"ja"},{"givenName":"ジュン","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"2999","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-28"}],"displaytype":"detail","filename":"Med_A640_abstract.pdf","filesize":[{"value":"72.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"内容の要旨","objectType":"abstract","url":"https://kagawa-u.repo.nii.ac.jp/record/265/files/Med_A640_abstract.pdf"},"version_id":"1930ea3f-5cc4-454a-ab4e-b93ae0eafecf"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-28"}],"displaytype":"detail","filename":"Med_A640_result.pdf","filesize":[{"value":"357.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"審査の結果の要旨","objectType":"other","url":"https://kagawa-u.repo.nii.ac.jp/record/265/files/Med_A640_result.pdf"},"version_id":"8d4aa842-8532-473c-af16-e92ad4a5abdb"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-28"}],"displaytype":"detail","filename":"Med_A640_summary.pdf","filesize":[{"value":"121.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"本文の要約","objectType":"summary","url":"https://kagawa-u.repo.nii.ac.jp/record/265/files/Med_A640_summary.pdf"},"version_id":"8ea7b7a4-2fa1-4921-af41-767b0871951e"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ATP-binding cassette, sub-family C, member 2","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"bilirubin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"children","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"coproporphyrin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"high-performance liquid chromatography","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Developmental characteristics of urinary coproporphyrin I/(I +III) ratio","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Developmental characteristics of urinary coproporphyrin I/(I +III) ratio","subitem_title_language":"en"}]},"item_type_id":"10006","owner":"11","path":["40"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-08-18"},"publish_date":"2017-08-18","publish_status":"0","recid":"265","relation_version_is_last":true,"title":["Developmental characteristics of urinary coproporphyrin I/(I +III) ratio"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2024-10-31T08:01:23.058769+00:00"}