@phdthesis{oai:kagawa-u.repo.nii.ac.jp:00000268,
 author = {Shinohara, Natsuyo and 篠原, 奈都代},
 month = {2020-10-29, 2020-10-29, 2020-10-29},
 note = {Background
The present study investigates the effects of d-allose, a rare sugar, on the inflammatory response after transient forebrain ischemia in the gerbil and whether it reduces oxidative stress (8-hydroxyl-2′-deoxyguanosine levels) and behavioral deficits., Methods
Transient forebrain ischemia was induced by occlusion of the bilateral common carotid arteries for 5 minutes. d-Allose was intraperitoneally injected immediately after ischemia (400 mg/kg). Inflammatory cytokines and oxidative damage in the hippocampus and behavioral deficits were examined 3 days after ischemia., Results
d-Allose administration reduced ischemia-induced cytokine production, oxidative stress, and behavioral deficits (motor and memory related)., Conclusions
The present results suggest that d-allose reduces brain injury after transient global ischemia by suppressing inflammation as well as by inhibiting oxidative stress.},
 school = {香川大学, Kagawa University},
 title = {D-allose attenuates overexpression of inflammatory cytokines after cerebral ischemia/reperfusion injury in gerbil},
 year = {},
 yomi = {シノハラ, ナツヨ}
}