{"created":"2023-05-15T09:41:12.836212+00:00","id":268,"links":{},"metadata":{"_buckets":{"deposit":"291fd064-453b-4144-88d7-690761194a9e"},"_deposit":{"created_by":11,"id":"268","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"268"},"status":"published"},"_oai":{"id":"oai:kagawa-u.repo.nii.ac.jp:00000268","sets":["13:40"]},"author_link":["1245"],"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2016-06-28"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"香川大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"Kagawa University"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"16201","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background\nThe present study investigates the effects of d-allose, a rare sugar, on the inflammatory response after transient forebrain ischemia in the gerbil and whether it reduces oxidative stress (8-hydroxyl-2′-deoxyguanosine levels) and behavioral deficits.","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"Methods\nTransient forebrain ischemia was induced by occlusion of the bilateral common carotid arteries for 5 minutes. d-Allose was intraperitoneally injected immediately after ischemia (400 mg/kg). Inflammatory cytokines and oxidative damage in the hippocampus and behavioral deficits were examined 3 days after ischemia.","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"Results\nd-Allose administration reduced ischemia-induced cytokine production, oxidative stress, and behavioral deficits (motor and memory related).","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"Conclusions\nThe present results suggest that d-allose reduces brain injury after transient global ischemia by suppressing inflammation as well as by inhibiting oxidative stress.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第643号"}]},"item_10006_relation_15":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.jstrokecerebrovasdis.2016.01.030","subitem_relation_type_select":"DOI"}},{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://dl.ndl.go.jp/pid/10952393","subitem_relation_type_select":"URI"}}]},"item_10006_relation_22":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"27342700","subitem_relation_type_select":"PMID"}}]},"item_10006_relation_28":{"attribute_name":"論文ID（NAID）","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"500001039463","subitem_relation_type_select":"NAID"}}]},"item_10006_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 2016 National Stroke Association. Published by Elsevier Inc. All rights reserved.","subitem_rights_language":"en"},{"subitem_rights":"This article is provided in the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (CC-BY-NC-ND 4.0) .https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja","subitem_rights_language":"en"}]},"item_10006_text_30":{"attribute_name":"KEID","attribute_value_mlt":[{"subitem_text_value":"27869"}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_fa2ee174bc00049f","subitem_version_type":"P"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Shinohara, Natsuyo","creatorNameLang":"en"},{"creatorName":"篠原, 奈都代","creatorNameLang":"ja"},{"creatorName":"シノハラ, ナツヨ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-29"}],"displaytype":"detail","filename":"Med_A643.pdf","filesize":[{"value":"371.5 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"本文","objectType":"fulltext","url":"https://kagawa-u.repo.nii.ac.jp/record/268/files/Med_A643.pdf"},"version_id":"14d11b40-92cc-4e84-b8b5-904192d5b301"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-29"}],"displaytype":"detail","filename":"Med_A643_abstract.pdf","filesize":[{"value":"72.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"内容の要旨","objectType":"abstract","url":"https://kagawa-u.repo.nii.ac.jp/record/268/files/Med_A643_abstract.pdf"},"version_id":"0967ebe4-29ea-4575-9db4-dee2f93a469b"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-10-29"}],"displaytype":"detail","filename":"Med_A643_result.pdf","filesize":[{"value":"446.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"審査の結果の要旨","objectType":"other","url":"https://kagawa-u.repo.nii.ac.jp/record/268/files/Med_A643_result.pdf"},"version_id":"0167fc89-503e-4d05-a03d-9cc4e5279842"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Ischemia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cytokines","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"d-allose","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hyperactivity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"inflammation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"oxidation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"reperfusion","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"D-allose attenuates overexpression of inflammatory cytokines after cerebral ischemia/reperfusion injury in gerbil","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"D-allose attenuates overexpression of inflammatory cytokines after cerebral ischemia/reperfusion injury in gerbil","subitem_title_language":"en"}]},"item_type_id":"10006","owner":"11","path":["40"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-08-21"},"publish_date":"2017-08-21","publish_status":"0","recid":"268","relation_version_is_last":true,"title":["D-allose attenuates overexpression of inflammatory cytokines after cerebral ischemia/reperfusion injury in gerbil"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2024-02-05T09:31:41.850918+00:00"}