{"created":"2023-05-15T09:43:20.775093+00:00","id":3570,"links":{},"metadata":{"_buckets":{"deposit":"521de0f8-aa60-4424-b220-73f913662e4f"},"_deposit":{"created_by":11,"id":"3570","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"3570"},"status":"published"},"_oai":{"id":"oai:kagawa-u.repo.nii.ac.jp:00003570","sets":["1:58:321:417"]},"author_link":["51","1664","2223","2933","650","2273"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-02-22","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"116","bibliographicPageEnd":"72","bibliographicPageStart":"67","bibliographicVolumeNumber":"63","bibliographic_titles":[{"bibliographic_title":"香川大学農学部学術報告","bibliographic_titleLang":"ja"},{"bibliographic_title":"Technical bulletin of Faculty of Agriculture, Kagawa University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Sesquiterpene lactones such as enhydrin, sonchifolin and uvedalin from yacon (Smallanthus sonchifolius) were extracted, purified by silica gel column chromatography, and then crystallized by acetone to get the higher purity of the sesquiterpene lactones. From the crude extracts by silica gel column chromatography, the sesquiterpene lactones of enhydrin (200mg), uvedalin (90mg), and sonchifolin (120mg) from 2.9g of crude extracts have successfully been purified the proper amounts of three sesquiterpene lactones by the combination with crystallizations and ptlc chromatographies. With this kind of short steps of purification, of three sesquiterpene lactones with higher purity (95%<) were isolated as higher activity component for anti‐deformation against Raji cells and Hela cells.","subitem_description_language":"en","subitem_description_type":"Abstract"},{"subitem_description":"ヤーコン（Smallanthus sonchifolius）葉に含まれるエンヒドリン、ウベダリン、ソンチホリンなどのセスキテルペンラクトンは抗発ガンプロモター活性を有するが、これらの成分をアセトン抽出後、シリカゲルクロマトグラフィー及びアセトンによる結晶化により、簡便に精製できることが分かった。2.9gのアセトン抽出物からエンヒドリン200mg、ウベダリン90mg、ソンチホリン120mgをジエチルエーテルとヘキサンを用いた結晶化とPTLCにより95%以上の純度で単離できた。","subitem_description_language":"ja","subitem_description_type":"Abstract"}]},"item_10002_heading_23":{"attribute_name":"見出し","attribute_value_mlt":[{"subitem_heading_banner_headline":"応用生物科学科","subitem_heading_headline":"生物資源利用学大講座","subitem_heading_language":"ja"},{"subitem_heading_banner_headline":"Department of Applied Biological Science","subitem_heading_headline":"Chair of Applied Bioresource Science","subitem_heading_language":"en"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"香川大学農学部","subitem_publisher_language":"ja"}]},"item_10002_relation_12":{"attribute_name":"論文ID（NAID）","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"120007012831","subitem_relation_type_select":"NAID"}}]},"item_10002_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://agriknowledge.affrc.go.jp/RN/2010811495","subitem_relation_type_select":"URI"}}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00038339","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0368-5128","subitem_source_identifier_type":"PISSN"}]},"item_10002_text_25":{"attribute_name":"WAID","attribute_value_mlt":[{"subitem_text_value":"51"}]},"item_10002_text_26":{"attribute_name":"KEID","attribute_value_mlt":[{"subitem_text_value":"27917"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Siriwan, Dalad","creatorNameLang":"ja"},{"creatorName":"シリワン, ダラ","creatorNameLang":"ja-Kana"},{"creatorName":"Siriwan, Dalad","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"51","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000018150348","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000018150348"}]},{"creatorNames":[{"creatorName":"成瀬, 孝行","creatorNameLang":"ja"},{"creatorName":"ナルセ, タカユキ","creatorNameLang":"ja-Kana"},{"creatorName":"Naruse, Takayuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"1664","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000018150349 ","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000018150349 "}]},{"creatorNames":[{"creatorName":"陳, 静波","creatorNameLang":"ja"},{"creatorName":"Chen, Jingbo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2223","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000018150350 ","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000018150350 "}]},{"creatorNames":[{"creatorName":"林, 加奈","creatorNameLang":"ja"},{"creatorName":"ハヤシ, カナ","creatorNameLang":"ja-Kana"},{"creatorName":"Hayashi, Kana","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2933","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000405431994 ","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000405431994 "}]},{"creatorNames":[{"creatorName":"近藤, 昭","creatorNameLang":"ja"},{"creatorName":"コンドウ, アキラ","creatorNameLang":"ja-Kana"},{"creatorName":"Kondo, Akira","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"650","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000405431995 ","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000405431995 "}]},{"creatorNames":[{"creatorName":"田村, 啓敏","creatorNameLang":"ja"},{"creatorName":"タムラ, ヒロトシ","creatorNameLang":"ja-Kana"},{"creatorName":"Tamura, Hirotoshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2273","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"9000396141539 ","nameIdentifierScheme":"CiNii ID","nameIdentifierURI":"http://ci.nii.ac.jp/nrid/9000396141539 "},{"nameIdentifier":"00188442","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=00188442"},{"nameIdentifier":"read0189028","nameIdentifierScheme":"researchmap","nameIdentifierURI":"https://researchmap.jp/read0189028"},{"nameIdentifier":"0000-0003-2412-9928","nameIdentifierScheme":"ORCID ID","nameIdentifierURI":"https://orcid.org/0000-0003-2412-9928"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-14"}],"displaytype":"detail","filename":"AN00038339_063_L067.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00038339_063_L067","objectType":"fulltext","url":"https://kagawa-u.repo.nii.ac.jp/record/3570/files/AN00038339_063_L067.pdf"},"version_id":"cb4ca461-198f-49c3-bdf6-12b1d04c3a84"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Smallanthus sonchifolius; crystallization","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Raji cells; Human Burkitt’s lymphoma cell","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"deformation; cancer prevention","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ヤーコン葉に含まれるラジ細胞（ヒトバーキットリンパ腫系細胞）の抗変形活性物質であるセスキテルペンラクトン類の迅速精製法","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヤーコン葉に含まれるラジ細胞（ヒトバーキットリンパ腫系細胞）の抗変形活性物質であるセスキテルペンラクトン類の迅速精製法","subitem_title_language":"ja"},{"subitem_title":"Rapid purification of sesquiterpene lactones, active chemicals for anti‐deformation of Raji cells (human Burkitt's lymphoma cell line) in yacon leaves","subitem_title_language":"en"},{"subitem_title":"ヤーコン ハ ニ フクマレル ラジサイボウ ヒト バーキット リンパシュケイ サイボウ ノ コウヘンケイ カッセイ ブッシツ デ アル セスキテルペンラクトンルイ ノ ジンソク セイセイ","subitem_title_language":"ja-Kana"}]},"item_type_id":"10002","owner":"11","path":["417"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-11-15"},"publish_date":"2017-11-15","publish_status":"0","recid":"3570","relation_version_is_last":true,"title":["ヤーコン葉に含まれるラジ細胞（ヒトバーキットリンパ腫系細胞）の抗変形活性物質であるセスキテルペンラクトン類の迅速精製法"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-10-17T07:21:59.662836+00:00"}