{"created":"2023-05-15T09:46:59.780995+00:00","id":8890,"links":{},"metadata":{"_buckets":{"deposit":"aa103db0-9fd6-4c13-854a-24b856d45412"},"_deposit":{"created_by":11,"id":"8890","owners":[11],"pid":{"revision_id":0,"type":"depid","value":"8890"},"status":"published"},"_oai":{"id":"oai:kagawa-u.repo.nii.ac.jp:00008890","sets":["13:40"]},"author_link":["3406"],"item_10006_alternative_title_1":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"脊髄上行路の形成過程における由来体節に基づく差違の解析","subitem_alternative_title_language":"ja"}]},"item_10006_date_granted_11":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2021-12-27"}]},"item_10006_degree_grantor_9":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"香川大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"Kagawa University"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"16201","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_10006_degree_name_8":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士（医学）","subitem_degreename_language":"ja"}]},"item_10006_description_7":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The present study aimed to assess spinal tract formation in neurons originating from cervical (C7), brachial (C14), and thoracic (T4) regions, with the lumbar (LS2) region as a reference, in a chick embryo. For the assessment of the spinal tracts, we introduced a vector expressing human placental alkaline phosphatase into progenitor cells generated after neural tube closure and belonging to the above segments, using in ovo electroporation. The ascending axons took primarily similar paths: dorsal commissural, ventral commissural, and dorsal non-commissural paths, with some variance depending on their originating segments. Some populations of non-commissural neurons later extended their axons following a ventral path. The elongation rates of these axons are primarily constant and tended to increase over time; however, some variations depending on the originating segments were also observed. Some of the dorsally ascending axons entered into the developing cerebellum, and spinocerebellar neurons originating from T4 projected their axons into the cortex of the cerebellum differently from those from LS2. These results unveil an overall picture of early ascending spinal tract formation.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_10006_dissertation_number_12":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第786号"}]},"item_10006_relation_15":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1016/j.brainres.2021.147595","subitem_relation_type_select":"DOI"}}]},"item_10006_relation_22":{"attribute_name":"PubMed番号","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"34332964","subitem_relation_type_select":"PMID"}}]},"item_10006_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 2021 Elsevier B.V. All rights reserved.","subitem_rights_language":"en"},{"subitem_rights":"Embergo expiration date: 2022-10-01","subitem_rights_language":"en"}]},"item_10006_version_type_18":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_fa2ee174bc00049f","subitem_version_type":"P"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"國土, 曜平","creatorNameLang":"ja"},{"creatorName":"コクド, ヨウヘイ","creatorNameLang":"ja-Kana"},{"creatorName":"Kokudo, Yohei","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-10-01"}],"displaytype":"detail","filename":"Med_A786.pdf","filesize":[{"value":"6.0 MB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"本文","objectType":"fulltext","url":"https://kagawa-u.repo.nii.ac.jp/record/8890/files/Med_A786.pdf"},"version_id":"05e52dc9-0cfc-4e7a-8849-8eaf2990ea6d"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-01-14"}],"displaytype":"detail","filename":"Med_A786_abstract.pdf","filesize":[{"value":"112.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"内容の要旨","objectType":"abstract","url":"https://kagawa-u.repo.nii.ac.jp/record/8890/files/Med_A786_abstract.pdf"},"version_id":"5c5c4ad8-07c4-45ee-8653-dcf3aab9c53b"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-01-14"}],"displaytype":"detail","filename":"Med_A786_result.pdf","filesize":[{"value":"160.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"審査の結果の要旨","objectType":"other","url":"https://kagawa-u.repo.nii.ac.jp/record/8890/files/Med_A786_result.pdf"},"version_id":"f1840e73-1035-41c5-9f15-399d5fa9339c"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Spinal neurons","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Spinal ascending tract","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Spinocerebellar tract","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"In ovo electroporation","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Ascending spinal tract formation in chick embryo originating from different spinal regions","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Ascending spinal tract formation in chick embryo originating from different spinal regions","subitem_title_language":"en"}]},"item_type_id":"10006","owner":"11","path":["40"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2022-01-14"},"publish_date":"2022-01-14","publish_status":"0","recid":"8890","relation_version_is_last":true,"title":["Ascending spinal tract formation in chick embryo originating from different spinal regions"],"weko_creator_id":"11","weko_shared_id":-1},"updated":"2023-10-16T02:30:46.932286+00:00"}