WEKO3
アイテム
{"_buckets": {"deposit": "fffd5605-a791-4915-9299-84c72388c85e"}, "_deposit": {"created_by": 11, "id": "157", "owners": [11], "pid": {"revision_id": 0, "type": "depid", "value": "157"}, "status": "published"}, "_oai": {"id": "oai:kagawa-u.repo.nii.ac.jp:00000157", "sets": ["40"]}, "author_link": ["3147"], "item_10006_alternative_title_1": {"attribute_name": "その他(別言語等)のタイトル", "attribute_value_mlt": [{"subitem_alternative_title": "急性心不全で入院となった患者における尿中アンジオテンシノーゲンと血中ヒト脳性ナトリウム利尿ペプチド前駆体N端フラグメントの経時的変化に関して", "subitem_alternative_title_language": "ja"}]}, "item_10006_date_granted_11": {"attribute_name": "学位授与年月日", "attribute_value_mlt": [{"subitem_dategranted": "2020-09-29"}]}, "item_10006_degree_grantor_9": {"attribute_name": "学位授与機関", "attribute_value_mlt": [{"subitem_degreegrantor": [{"subitem_degreegrantor_language": "ja", "subitem_degreegrantor_name": "香川大学"}, {"subitem_degreegrantor_language": "en", "subitem_degreegrantor_name": "Kagawa University"}], "subitem_degreegrantor_identifier": [{"subitem_degreegrantor_identifier_name": "16201", "subitem_degreegrantor_identifier_scheme": "kakenhi"}]}]}, "item_10006_degree_name_8": {"attribute_name": "学位名", "attribute_value_mlt": [{"subitem_degreename": "博士(医学)", "subitem_degreename_language": "ja"}]}, "item_10006_description_7": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Objective: Home care is important in patients with heart failure (HF) in order to maintain their quality of life. A biomarker that can be measured noninvasively is needed to optimize the home care of patients with HF. Urinary angiotensinogen (uAGT) is an indicator of the intrarenal renin-angiotensin system activity, which may be augmented in HF. We hypothesized that uAGT might be a urinary biomarker in HF.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}, {"subitem_description": "Methods: We measured uAGT by an enzyme-linked immunosorbent assay and uAGT normalized by urinary creatinine (uCr)-designated uAGT/uCr-at admission and discharge in 45 patients hospitalized for HF.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}, {"subitem_description": "Results: We found that both uAGT/uCr [median (interquartile range): 65.5 (17.1-127.7) μg/g Cr at admission; 12.1 (6.0-37.0) μg/g Cr at discharge; p\u003c0.01] and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels [5,422 (2,280-9,907) pg/mL at admission; 903 (510-1,729) pg/mL at discharge; p\u003c0.01] significantly decreased between admission and discharge along with an improvement in patient\u0027s clinical status [New York Heart Association scores: 3 (3-4) at admission; 1 (1-1) at discharge; p\u003c0.01]. The generalized least squares model revealed that the time course changes in uAGT/uCr also correlated with those in NT-proBNP levels between admission and readmission in five patients readmitted for HF.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}, {"subitem_description": "Conclusion: The results indicated that the time course changes in uAGT/uCr correlated with those in the NT-proBNP levels in patients with HF who showed a clinical improvement. Further investigation and development of a kit for the rapid measurement of uAGT are needed to evaluate the clinical utility of uAGT as a biomarker in HF.", "subitem_description_language": "en", "subitem_description_type": "Abstract"}]}, "item_10006_dissertation_number_12": {"attribute_name": "学位授与番号", "attribute_value_mlt": [{"subitem_dissertationnumber": "甲第757号"}]}, "item_10006_relation_15": {"attribute_name": "関連サイト", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://doi.org/10.2169/internalmedicine.5212-20", "subitem_relation_type_select": "DOI"}}, {"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://dl.ndl.go.jp/pid/11583124", "subitem_relation_type_select": "URI"}}, {"subitem_relation_type": "hasVersion", "subitem_relation_type_id": {"subitem_relation_type_id_text": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725623/", "subitem_relation_type_select": "URI"}}]}, "item_10006_relation_22": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "33191370", "subitem_relation_type_select": "PMID"}}]}, "item_10006_relation_28": {"attribute_name": "論文ID(NAID)", "attribute_value_mlt": [{"subitem_relation_type_id": {"subitem_relation_type_id_text": "130007939852", "subitem_relation_type_select": "NAID"}}]}, "item_10006_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "Copyright © 2020 by The Japanese Society of Internal Medicine", "subitem_rights_language": "en"}]}, "item_10006_text_30": {"attribute_name": "KEID", "attribute_value_mlt": [{"subitem_text_value": "29129"}]}, "item_10006_version_type_18": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_fa2ee174bc00049f", "subitem_version_type": "P"}]}, "item_access_right": {"attribute_name": "アクセス権", "attribute_value_mlt": [{"subitem_access_right": "open access", "subitem_access_right_uri": "http://purl.org/coar/access_right/c_abf2"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yokoyama, Shota", "creatorNameLang": "en"}, {"creatorName": "横山, 聖太", "creatorNameLang": "ja"}, {"creatorName": "ヨコヤマ, ショウタ", "creatorNameLang": "ja-Kana"}], "nameIdentifiers": [{"nameIdentifier": "3147", "nameIdentifierScheme": "WEKO"}, {"nameIdentifier": "9000391376308", "nameIdentifierScheme": "CiNii ID", "nameIdentifierURI": "http://ci.nii.ac.jp/nrid/9000391376308"}, {"nameIdentifier": "10801392", "nameIdentifierScheme": "e-Rad", "nameIdentifierURI": "https://kaken.nii.ac.jp/ja/search/?qm=10801392"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-11-16"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Med_A757.pdf", "filesize": [{"value": "637.1 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 637100.0, "url": {"label": "本文", "objectType": "fulltext", "url": "https://kagawa-u.repo.nii.ac.jp/record/157/files/Med_A757.pdf"}, "version_id": "e7f67aff-7f31-4f6c-8510-8cddddeaf0e3"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-10-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 1, "filename": "Med_A757_abstract.pdf", "filesize": [{"value": "44.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 44900.0, "url": {"label": "内容の要旨", "objectType": "abstract", "url": "https://kagawa-u.repo.nii.ac.jp/record/157/files/Med_A757_abstract.pdf"}, "version_id": "cdb5eaf9-110b-4f70-acaf-5d4bea4a61df"}, {"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-10-20"}], "displaytype": "detail", "download_preview_message": "", "file_order": 2, "filename": "Med_A757_result.pdf", "filesize": [{"value": "81.7 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_note", "mimetype": "application/pdf", "size": 81700.0, "url": {"label": "審査の結果の要旨", "objectType": "other", "url": "https://kagawa-u.repo.nii.ac.jp/record/157/files/Med_A757_result.pdf"}, "version_id": "1955ebbc-78e5-4ded-a040-b1fa96c025d3"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "heart failure", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "renin-angiotensin system", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "urinary angiotensinogen", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}, {"subitem_subject": "N-terminal pro-B-typenatriuretic peptide", "subitem_subject_language": "en", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "doctoral thesis", "resourceuri": "http://purl.org/coar/resource_type/c_db06"}]}, "item_title": "Time Course Changes in Urinary Angiotensinogen and Circulating N-Terminal Pro-B-Type Natriuretic Peptide in Patients Hospitalized With Acute Heart Failure", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Time Course Changes in Urinary Angiotensinogen and Circulating N-Terminal Pro-B-Type Natriuretic Peptide in Patients Hospitalized With Acute Heart Failure", "subitem_title_language": "en"}]}, "item_type_id": "10006", "owner": "11", "path": ["40"], "permalink_uri": "https://kagawa-u.repo.nii.ac.jp/records/157", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2020-10-20"}, "publish_date": "2020-10-20", "publish_status": "0", "recid": "157", "relation": {}, "relation_version_is_last": true, "title": ["Time Course Changes in Urinary Angiotensinogen and Circulating N-Terminal Pro-B-Type Natriuretic Peptide in Patients Hospitalized With Acute Heart Failure"], "weko_shared_id": -1}
Time Course Changes in Urinary Angiotensinogen and Circulating N-Terminal Pro-B-Type Natriuretic Peptide in Patients Hospitalized With Acute Heart Failure
https://kagawa-u.repo.nii.ac.jp/records/157
https://kagawa-u.repo.nii.ac.jp/records/15718c4d2a1-60ce-4241-be14-9f45017e2bba
名前 / ファイル | ライセンス | アクション |
---|---|---|
本文 (637.1 kB)
|
|
|
内容の要旨 (44.9 kB)
|
|
|
審査の結果の要旨 (81.7 kB)
|
|
Item type | 学位論文 / Thesis or Dissertation(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2020-10-20 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Time Course Changes in Urinary Angiotensinogen and Circulating N-Terminal Pro-B-Type Natriuretic Peptide in Patients Hospitalized With Acute Heart Failure | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | 急性心不全で入院となった患者における尿中アンジオテンシノーゲンと血中ヒト脳性ナトリウム利尿ペプチド前駆体N端フラグメントの経時的変化に関して | |||||
言語 | ja | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
横山, 聖太
× 横山, 聖太 |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective: Home care is important in patients with heart failure (HF) in order to maintain their quality of life. A biomarker that can be measured noninvasively is needed to optimize the home care of patients with HF. Urinary angiotensinogen (uAGT) is an indicator of the intrarenal renin-angiotensin system activity, which may be augmented in HF. We hypothesized that uAGT might be a urinary biomarker in HF. | |||||
言語 | en | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Methods: We measured uAGT by an enzyme-linked immunosorbent assay and uAGT normalized by urinary creatinine (uCr)-designated uAGT/uCr-at admission and discharge in 45 patients hospitalized for HF. | |||||
言語 | en | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Results: We found that both uAGT/uCr [median (interquartile range): 65.5 (17.1-127.7) μg/g Cr at admission; 12.1 (6.0-37.0) μg/g Cr at discharge; p<0.01] and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels [5,422 (2,280-9,907) pg/mL at admission; 903 (510-1,729) pg/mL at discharge; p<0.01] significantly decreased between admission and discharge along with an improvement in patient's clinical status [New York Heart Association scores: 3 (3-4) at admission; 1 (1-1) at discharge; p<0.01]. The generalized least squares model revealed that the time course changes in uAGT/uCr also correlated with those in NT-proBNP levels between admission and readmission in five patients readmitted for HF. | |||||
言語 | en | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Conclusion: The results indicated that the time course changes in uAGT/uCr correlated with those in the NT-proBNP levels in patients with HF who showed a clinical improvement. Further investigation and development of a kit for the rapid measurement of uAGT are needed to evaluate the clinical utility of uAGT as a biomarker in HF. | |||||
言語 | en | |||||
学位名 | ||||||
言語 | ja | |||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
識別子Scheme | kakenhi | |||||
識別子 | 16201 | |||||
言語 | ja | |||||
機関名 | 香川大学 | |||||
言語 | en | |||||
機関名 | Kagawa University | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2020-09-29 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲第757号 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | Copyright © 2020 by The Japanese Society of Internal Medicine | |||||
論文ID(NAID) | ||||||
識別子タイプ | NAID | |||||
関連識別子 | 130007939852 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 33191370 | |||||
関連サイト | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.2169/internalmedicine.5212-20 | |||||
関連サイト | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | URI | |||||
関連識別子 | https://dl.ndl.go.jp/pid/11583124 | |||||
関連サイト | ||||||
関連タイプ | hasVersion | |||||
識別子タイプ | URI | |||||
関連識別子 | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725623/ | |||||
著者版フラグ | ||||||
出版タイプ | P | |||||
出版タイプResource | http://purl.org/coar/version/c_fa2ee174bc00049f | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | heart failure | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | renin-angiotensin system | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | urinary angiotensinogen | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | N-terminal pro-B-typenatriuretic peptide | |||||
KEID | ||||||
29129 |