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Endoscopic ligation with O-ring closure for mucosal defects after rectal endoscopic submucosal dissection : A feasibility study (with video)
https://kagawa-u.repo.nii.ac.jp/records/11723
https://kagawa-u.repo.nii.ac.jp/records/11723dd24a2f4-0c48-483e-9371-886de80bb00b
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本文 (10.6 MB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2023-04-24 | |||||
タイトル | ||||||
タイトル | Endoscopic ligation with O-ring closure for mucosal defects after rectal endoscopic submucosal dissection : A feasibility study (with video) | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
その他(別言語等)のタイトル | ||||||
その他のタイトル | 直腸内視鏡的粘膜下層剥離術後の粘膜欠損に対するOリングを用いた内視鏡的結紮閉鎖術の有効性の検討 | |||||
言語 | ja | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
多田, 尚矢
× 多田, 尚矢 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Introduction: Mucosal defect closure after colorectal endoscopic submucosal dissection (ESD) may prevent post-ESD adverse events. Delayed bleeding is a particular concern in the rectum due to the presence of numerous blood vessels. However, rectal defect closure often fails due to the thick rectal wall. This study aimed to examine the feasibility of our newly developed endoscopic ligation with O-ring closure (E-LOC) for defects after rectal ESD. | |||||
言語 | en | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Methods: This was a prospective observational study conducted at a single institution. After excluding 2 patients with tumors mostly extending into the anal canal, the study cohort comprised 30 consecutive patients who underwent ESD of rectal neoplasms between July 2020 and July 2021. E-LOC using an endoscopic variceal ligation device was performed for closing mucosal defects after rectal ESD. The primary outcome was the complete closure rate. The secondary outcomes were the delayed bleeding rate, E-LOC procedure time, sustained closure rates on postoperative day (POD) 3, and E-LOC-associated complications. | |||||
言語 | en | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Results: Complete closure of the defect (median defect size 29.0 mm) was successfully achieved in 24 cases (80%). Delayed bleeding occurred in one case with incomplete closure (3.3%). The median E-LOC procedure time was 25.5 min (interquartile range, 20.0–30.0 min). The sustained closure rates were 83.3% (20/24) on POD 3 in the 24 cases with complete closure. No E-LOC-associated complications occurred. | |||||
言語 | en | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Discussion/Conclusions: E-LOC was feasible for defect closure after rectal ESD, and probably led to a decreased incidence of delayed bleeding. | |||||
言語 | en | |||||
学位名 | ||||||
言語 | ja | |||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 16201 | |||||
言語 | ja | |||||
学位授与機関名 | 香川大学 | |||||
言語 | en | |||||
学位授与機関名 | Kagawa University | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2023-03-24 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲第826号 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | © 2023 S. Karger AG, Basel | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 36630931 | |||||
関連サイト | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1159/000528348 | |||||
著者版フラグ | ||||||
出版タイプ | P | |||||
出版タイプResource | http://purl.org/coar/version/c_fa2ee174bc00049f | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Rectal endoscopic submucosal dissection | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Mucosal defect closure | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Postoperative adverse events |