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Using natural language processing techniques to detect adverse events from progress notes due to chemotherapy
https://kagawa-u.repo.nii.ac.jp/records/11730
https://kagawa-u.repo.nii.ac.jp/records/11730b03aa7d5-a719-4677-b6dd-95317888b086
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||||||||
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公開日 | 2023-04-25 | |||||||||||
タイトル | ||||||||||||
タイトル | Using natural language processing techniques to detect adverse events from progress notes due to chemotherapy | |||||||||||
言語 | en | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||||
資源タイプ | doctoral thesis | |||||||||||
その他(別言語等)のタイトル | ||||||||||||
その他のタイトル | がん薬物療法に関する経過記録からの自然言語処理を用いた有害事象検出 | |||||||||||
言語 | ja | |||||||||||
アクセス権 | ||||||||||||
アクセス権 | open access | |||||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
著者 |
間島, 行則
× 間島, 行則
WEKO
4118
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Objective: In recent years, natural language processing (NLP) techniques have progressed, and their application in the medical field has been tested. However, the use of NLP to detect symptoms from medical progress notes written in Japanese, remains limited. We aimed to detect 2 gastrointestinal symptoms that interfere with the continuation of chemotherapy-nausea/vomiting and diarrhea-from progress notes using NLP, and then to analyze factors affecting NLP. | |||||||||||
言語 | en | |||||||||||
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内容記述タイプ | Abstract | |||||||||||
内容記述 | Materials and methods: In this study, 200 patients were randomly selected from 5277 patients who received intravenous injections of cytotoxic anticancer drugs at Kagawa University Hospital, Japan, between January 2011 and December 2018. We aimed to detect the first occurrence of nausea/vomiting (Group A) and diarrhea (Group B) using NLP. The NLP performance was evaluated by the concordance with a review of the physicians' progress notes used as the gold standard. | |||||||||||
言語 | en | |||||||||||
抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Results: Both groups showed high concordance: 83.5% (95% confidence interval [CI] 74.1-90.1) in Group A and 97.7% (95% CI 91.3-99.9) in Group B. However, the concordance was significantly better in Group B (P = .0027). There were significantly more misdetection cases in Group A than in Group B (15.3% in Group A; 1.2% in Group B, P = .0012) due to negative findings or past history. | |||||||||||
言語 | en | |||||||||||
抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Conclusion: We detected occurrences of nausea/vomiting and diarrhea accurately using NLP. However, there were more misdetection cases in Group A due to negative findings or past history, which may have been influenced by the physicians' more frequent documentation of nausea/vomiting. | |||||||||||
言語 | en | |||||||||||
学位名 | ||||||||||||
言語 | ja | |||||||||||
学位名 | 博士(医学) | |||||||||||
学位授与機関 | ||||||||||||
学位授与機関識別子Scheme | kakenhi | |||||||||||
学位授与機関識別子 | 16201 | |||||||||||
言語 | ja | |||||||||||
学位授与機関名 | 香川大学 | |||||||||||
言語 | en | |||||||||||
学位授与機関名 | Kagawa University | |||||||||||
学位授与年月日 | ||||||||||||
学位授与年月日 | 2023-03-24 | |||||||||||
学位授与番号 | ||||||||||||
学位授与番号 | 甲第833号 | |||||||||||
権利 | ||||||||||||
言語 | en | |||||||||||
権利情報 | © The Author(s) 2022. | |||||||||||
権利 | ||||||||||||
言語 | en | |||||||||||
権利情報 | The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study was supported by Daiichi Sankyo Co., Ltd. | |||||||||||
権利 | ||||||||||||
言語 | en | |||||||||||
権利情報Resource | https://creativecommons.org/licenses/by-nc/4.0/ | |||||||||||
権利情報 | This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). Request permissions for this article. | |||||||||||
PubMed番号 | ||||||||||||
識別子タイプ | PMID | |||||||||||
関連識別子 | 35342285 | |||||||||||
関連サイト | ||||||||||||
関連タイプ | isVersionOf | |||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | https://doi.org/10.1177/11769351221085064 | |||||||||||
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関連タイプ | hasVersion | |||||||||||
識別子タイプ | URI | |||||||||||
関連識別子 | http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8943584/ | |||||||||||
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出版タイプ | P | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_fa2ee174bc00049f | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | Natural language processing | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | data mining | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | electronic health records | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | progress notes | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | drug therapy | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | pharmacovigilance | |||||||||||
キーワード | ||||||||||||
言語 | en | |||||||||||
主題Scheme | Other | |||||||||||
主題 | drug-related side effects and adverse reactions |