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3D power Doppler ultrasound assessment of placental perfusion during uterine contraction in labor
https://kagawa-u.repo.nii.ac.jp/records/284
https://kagawa-u.repo.nii.ac.jp/records/2843e1908f9-bd1c-4632-a62b-c9356a5ab342
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本文 (1.8 MB)
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審査の結果の要旨 (437.5 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2017-08-25 | |||||
タイトル | ||||||
タイトル | 3D power Doppler ultrasound assessment of placental perfusion during uterine contraction in labor | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
佐藤, 美樹
× 佐藤, 美樹 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Introduction To assess placental perfusion during spontaneous or induced uterine contraction in labor at term using placental vascular sonobiopsy (PVS) by 3D power Doppler ultrasound with the VOCAL imaging analysis program. |
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言語 | en | |||||
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内容記述タイプ | Abstract | |||||
内容記述 | Method PVS was performed in 50 normal pregnancies (32 in spontaneous labor group [SLG], and 18 in induced labor group with oxytocin or prostaglandin F2α [ILG]) at 37–41 weeks of gestation to assess placental perfusion during uterine contraction in labor. Only pregnancies with an entirely visualized anterior placenta were included in the study. Data acquisition was performed before, during (at the peak of contraction), and after uterine contraction. 3D power Doppler indices such as the vascularization index (VI), flow index (FI), and vascularization flow index (VFI) were calculated in each placenta. |
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言語 | en | |||||
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内容記述タイプ | Abstract | |||||
内容記述 | Results There were no abnormal fetal heart rate tracings during contraction in either group. VI and VFI values were significantly reduced during uterine contraction in both groups (SLG, −33.4% [−97.0–15.2%], and ILG, −49.6% [−78.2–−4.0%]), respectively (P < 0.001). The FI value in the ILG group was significantly lower during uterine contraction (P = 0.035), whereas it did not change during uterine contraction in the SLG group. After uterine contraction, all vascular indices returned almost to the same level as that before uterine contraction. However, the FI value in ILG (−8.6%, [−19.7–16.0%]) was significantly lower than that in SLG (2.4%, [−13.4–38.1%]) after uterine contraction (P < 0.05). All 3D power Doppler indices (VI, FI, and VFI) during uterine contraction (at the peak of contraction) showed a correlation greater than 0.7, with good intra- and inter-observer agreements. |
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言語 | en | |||||
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内容記述タイプ | Abstract | |||||
内容記述 | Discussion Our findings suggest that uterine contraction in both spontaneous and induced labors causes a significant reduction in placental perfusion. Reduced placental blood flow in induced uterine contraction has a tendency to be marked compared with that in spontaneous uterine contraction. To the best of our knowledge, this is the first study on the non-invasive assessment of placental perfusion during uterine contraction in labor using 3D power Doppler ultrasound. However, the data and their interpretation in the present study should be taken with some degree of caution because of the small number of subjects studied. Further studies involving a larger sample size are needed to assess placental perfusion and vascularity using PVS during normal and abnormal uterine contractions in normal and high-risk pregnancies. |
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言語 | en | |||||
学位名 | ||||||
言語 | ja | |||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 16201 | |||||
言語 | ja | |||||
学位授与機関名 | 香川大学 | |||||
言語 | en | |||||
学位授与機関名 | Kagawa University | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2017-03-24 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲第664号 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | © 2016 Elsevier Ltd. All rights reserved. | |||||
論文ID(NAID) | ||||||
識別子タイプ | NAID | |||||
関連識別子 | 500001039440 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 27577707 | |||||
関連サイト | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.1016/j.placenta.2016.06.018 | |||||
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関連タイプ | isIdenticalTo | |||||
識別子タイプ | URI | |||||
関連識別子 | https://dl.ndl.go.jp/pid/10952408 | |||||
著者版フラグ | ||||||
出版タイプ | P | |||||
出版タイプResource | http://purl.org/coar/version/c_fa2ee174bc00049f | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Placental vascular sonobiopsy | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | 3D power Doppler ultrasound | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Placental perfusion | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Spontaneous uterine contraction | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Induced uterine contraction | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Labor | |||||
KEID | ||||||
値 | 27885 |