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Antimicrobial activity and stability of weakly acidified chlorous acid water
https://kagawa-u.repo.nii.ac.jp/records/382
https://kagawa-u.repo.nii.ac.jp/records/38252d5b00b-8ea9-4621-8548-b6b317c9951f
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内容の要旨 (82.2 kB)
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審査の結果の要旨 (558.6 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2019-07-16 | |||||
タイトル | ||||||
タイトル | Antimicrobial activity and stability of weakly acidified chlorous acid water | |||||
言語 | en | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
堀内, 功典
× 堀内, 功典 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The antimicrobial activity of weakly acidified chlorous acid water (WACAW) against Staphylococcus aureus, non-pathogenic Escherichia coli, enterohemorrhagic E. coli (EHEC O157:H7), Candida albicans, and spore-forming Bacillus and Paenibacillus species was evaluated in vitro. The antiviral activity was also examined using feline calicivirus (FCV). Diluted WACAW (>100 ppm) effectively reduced the number of non-spore-forming bacteria (>4 log10 CFU reductions) within 5 min. Treatment with this sanitizer at 400 ppm for 30 min achieved>5 log10 CFU reductions in spore-forming Bacillus and Paenibacillus species while an equivalent concentration of sodium hypochlorite (NaClO) resulted in only a 0.98 and 2.72 log10 CFU reduction, respectively. The effect of this sanitizer against FCV was equivalent to that of NaClO. Immersion in WACAW (400 ppm) achieved >4 and 2.26 log10 CFU reductions in Campylobacter jejuni and EHEC, respectively, on artificially contaminated broiler carcass pieces. Finally, theantimicrobial activity of this sanitizer was shown to be maintained for at least 28 d when in contact with nonwoven fabric (100% cotton). This study showed that pH control of chlorous acid is expected to modify its antimicrobial activity and stability. WACAW is expected to have applications in various settings such as the food processing and healthcare industries. | |||||
言語 | en | |||||
学位名 | ||||||
言語 | ja | |||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 16201 | |||||
言語 | ja | |||||
学位授与機関名 | 香川大学 | |||||
言語 | en | |||||
学位授与機関名 | Kagawa University | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2016-03-24 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲第628号 | |||||
権利 | ||||||
言語 | en | |||||
権利情報 | Copyright © 2015 The Society for Antibacterial and Antifungal Agents, Japan | |||||
論文ID(NAID) | ||||||
識別子タイプ | NAID | |||||
関連識別子 | 500001356638 | |||||
PubMed番号 | ||||||
識別子タイプ | PMID | |||||
関連識別子 | 25817812 | |||||
関連サイト | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | https://doi.org/10.4265/bio.20.43 | |||||
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関連タイプ | isIdenticalTo | |||||
識別子タイプ | URI | |||||
関連識別子 | https://dl.ndl.go.jp/pid/11337633 | |||||
著者版フラグ | ||||||
出版タイプ | P | |||||
出版タイプResource | http://purl.org/coar/version/c_fa2ee174bc00049f | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Chlorous acid water | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Weak acidification | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Broiler carcasses | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | Stability in fabrics | |||||
KEID | ||||||
値 | 28746 |